Plasmid-Borne Antimicrobial Resistance of Staphylococcus aureus Isolated in a Hospital in Lisbon, Portugal
- Authors: Costa Sofia Santos, Couto Isabel, Fessler Andrea T., Kadlec Kristina, Melo-Cristino José, Palma Cláudia, Schwarz Stefan, Viveiros Miguel
- Publication Year: 2016
- Journal: Microbial Drug Resistance
- Link: http://online.liebertpub.com/doi/abs/10.1089/mdr.2015.0352
Plasmids play a key role in the genetic plasticity and survival of Staphylococcus aureus in challenging environments. Although many S. aureus plasmids have been described, still few studies portray the plasmid content of a given S. aureus population. The aim of this work was to characterize the plasmids carried by a collection of 53 S. aureus isolates collected in a large hospital in Lisbon, Portugal, and investigate their role in conferring resistance to several antimicrobial agents.