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Identification of trypanosomatids and blood feeding preferences of phlebotomine sand fly species common in Sicily, Southern Italy

In this study, the presence of Leishmania DNA and blood feeding sources in phlebotomine sand fly species commonly present in Sicily were investigated. A total of 1,866 female sand flies including 176 blood fed specimens were sampled over two seasons in five selected sites in Sicily (southern Italy). Sergentomyia minuta (n = 1,264) and Phlebotomus […]
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Potential of the natural products against leishmaniasis in Old World – a review of in-vitro studies

Leishmaniasis is a vector-borne disease among the 10 most Neglected Tropical Diseases with diverse clinical manifestations caused by protozoan parasites of the Leishmania genus. Around 80% of leishmaniasis cases are found in the Old World affecting populations mainly in low and middle-income countries. Its control relies mostly on chemotherapy which still presents many drawbacks. Natural […]
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Monitoring Leishmania infection and exposure to Phlebotomus perniciosus using minimal and non-invasive canine samples

Background: In endemic areas of zoonotic leishmaniosis caused by L. infantum, early detection of Leishmania infection in dogs is essential to control the dissemination of the parasite to humans. The aim of this study was to evaluate the serological and/or molecular diagnostic performance of minimally and non-invasive samples (conjunctiva cells (CS) and peripheral blood (PB)) […]
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Effects of covid-19 infection during pregnancy and neonatal prognosis: what is the evidence?

Background: Little is known about how COVID-19 infection affects pregnant women, as well as about the possibility of vertical transmission or that of premature labor. Thus, this study’s objective was to identify existing evidence to directive public policies. Method: Systematic literature review assessing papers published in the most comprehensive databases in the field of health. […]
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Using hospital auxiliary worker and 24-h TB services as potential tools to overcome inhospital TB delays: a quasi-experimental study

Background: In-hospital logistic management barriers (LMB) are considered to be important risk factors for delays in TB diagnosis and treatment initiation (TB-dt), which perpetuates TB transmission and the development of TB morbidity and mortality. We assessed the contribution of hospital auxiliary workers (HAWs) and 24-h TB laboratory services using Xpert (24h-Xpert) on the delays in […]
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Risk of Readmission Among HIV Patients in Public Portuguese Hospitals: Longitudinal Multilevel Population-Based Study

Background: Thirty-day hospital readmission is receiving growing attention as an indicator of the quality of hospital care. Understanding factors associated with 30-day hospital readmission among HIV patients in Portugal is essential given the high burden cost of HIV hospitalizations in Portugal, a country suffering from financial constrains for almost 10 years. Objectives: We aimed to […]
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Quantitative Proteomics Identifies Metabolic Pathways Affected by Babesia Infection and Blood Feeding in the Sialoproteome of the Vector Rhipicephalus bursa

O trabalho têm como foco o estudo de interações entre vector e parasita, Rhipicephalus bursa e Babesia ovis, com o objectivo de identificar novos alvos para o desenvolvimentos de vacinas e outras estratégias de controlo de carraças e doenças transmitidas pelas mesmas.
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National TB program shortages as potential factor for poor-quality TB care cascade: Healthcare workers’ perspective from Beira, Mozambique

Background Mozambique is one of the countries with the deadly implementation gaps in the tuberculosis (TB) care and services delivery. In-hospital delays in TB diagnosis and treatment, transmission and mortality still persist, in part, due to poor-quality of TB care cascade. Objective We aimed to assess, from the healthcare workers’ (HCW) perspective, factors associated with […]
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Financing healthcare in low-income developing countries: A challenge for equity in health

Um dos desafios dos países de baixa renda é a crescente procura de cuidados de saúde de qualidade em contextos em que os Governos são incapazes de garantir o financiamento adequado dos sistemas de saúde. Embora cada país viva a sua própria conjuntura, todos eles estão empenhados na “cobertura universal em saúde”; necessitando de melhorar a equidade no acesso aos cuidados e a eficiência na gestão dos recursos atribuídos à saúde. O […]
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Garantia de Direitos e Regulação: Perspetivas de Direito Administrativo

O professor da Unidade de Saúde Pública Internacional e Bioestatística, do Instituto de Higiene e Medicina Tropical, Jorge Simões, participou com um capítulo intitulado “Regulação em Saúde” no livro “Garantia de Direitos e Regulação: Perspetivas de Direito Administrativo”. A regulação na saúde assume diversas formas consoante a perceção assumida em cada um dos países. A […]
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