Evidence of significant synergism between antibiotics and the antipsychotic, antimicrobial drug flupenthixol.
- Autores: Amaral L, Dasgupta A, Dastidar SG, Jeyaseeli L, Molnar J
- Ano de Publicação: 2012
- Journal: European Journal of Clinical Microbiology & Infectious Diseases
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Evidences+of+Significant+Synergism+between+Antibiotics+and+the+Antipsychotic+Antimicrobial+Drug+Flupenthixol.
Previously, the antipsychotic, non-antibiotic compound flupenthixol dihydrochloride (Fp) was shown to exhibit distinct in vitro antibacterial activity against Gram-positive and Gram-negative bacteria and to significantly protect Swiss albino mice challenged with a known mouse virulent salmonella.