Immunization with the Leishmania infantum recombinant cyclophilin protein 1 confers partial protection to subsequent parasite infection and generates specific memory T cells
- Autores: Alexandre-Pires G, Carreira J, Carvalho S, Rodrigues A, Santos-Gomes GM, Teixeira F
- Ano de Publicação: 2014
- Journal: Vaccine
- Link: http://www.ncbi.nlm.nih.gov/pubmed/24486368
Control of zoonotic visceral leishmaniosis can be achieved using several available drugs. These drugs present high toxicity and require longer treatment regimens which complicate compliance to the treatment. Other control measures directed to the vector or the reservoirs are useful tools to restrain the spreading of this disease but the effects are transitory.