Evaluation of the automatic editing tool RECall for HIV-1 pol and V3 loop sequences
- Autores: Megens S, Schrooten Y, Van Laethem K, Vandamme AM, Vinken L
- Ano de Publicação: 2013
- Journal: Journal of Virological Methods
- Link: http://www.ncbi.nlm.nih.gov/pubmed/23748120
Genotypic drug resistance testing is routine practice in HIV-1 clinical care. The visual interpretation of sequencing electropherograms is labour-intensive and subject to intra- and inter-assay variability because decisions are based on operators’ judgments. In this study the performance of the automatic editing tool RECall was compared to the current standard of editing manually and editing using the tool ViroSeq.