Solute carriers affect Anopheles stephensi survival and Plasmodium berghei infection in the salivary glands

Autores: Antunes S, Couto J, de la Fuente J, Do Rosário V, Domingos A, Pinheiro-Silva R
Ano de Publicação: 2017
Journal: Scientific Reports
Link: https://www.ncbi.nlm.nih.gov/pubmed/28733628

Malaria is caused by mosquito-borne Plasmodium spp. parasites that must infect and survive within mosquito salivary glands (SGs) prior to host transmission. Recent advances in transcriptomics and the complete genome sequencing of mosquito vectors have increased our knowledge of the SG genes and proteins involved in pathogen infection and transmission.
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Mosquito Akirin as a potential antigen for malaria control

Recent evidences using Subolesin (SUB) and Akirin (AKR) vaccines showed a reduction in the survival and/or fertility of blood-sucking ectoparasite vectors and the infection with vector-borne pathogens. These experiments suggested the possibility of using AKR for malaria control.
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Solute carriers affect Anopheles stephensi survival and Plasmodium berghei infection in the salivary glands

Mosquito Akirin as a potential antigen for malaria control

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