Making a meal of it: mosquito spit protein controls blood feeding
Researchers led by Kanazawa University developed a transgenic approach to inactivating the mosquito salivary protein AAPP.
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Scientific Reports
Solute carriers affect Anopheles stephensi survival and Plasmodium berghei infection in the salivary glands
Malaria is caused by mosquito-borne Plasmodium spp. parasites that must infect and survive within mosquito salivary glands (SGs) prior to host transmission. Recent advances in transcriptomics and the complete genome sequencing of mosquito vectors have increased our knowledge of the SG genes and proteins involved in pathogen infection and transmission.
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Massive introgression drives species radiation at the range limit of Anopheles gambiae
Impacts of introgressive hybridisation may range from genomic erosion and species collapse to rapid adaptation and speciation but opportunities to study these dynamics are rare. We investigated the extent, causes and consequences of a hybrid zone between Anopheles coluzzii and Anopheles gambiae in Guinea-Bissau, where high hybridisation rates appear to be stable at least since the 1990s.Anopheles gambiae was genetically partitioned into inland and coastal subpopulations, separated by a central region dominated by A. coluzzii.
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Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola
Tuberculosis (TB) poses a serious public health problem in Angola. No surveillance data on drug resistance is available and nothing is known regarding the genetic diversity and population structure of circulating Mycobacterium tuberculosis strains. Here, we have genotyped and evaluated drug susceptibility of 89 Mycobacterium tuberculosis clinical isolates from Luanda.
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Serological diagnosis of pneumocystosis: production of a synthetic recombinant antigen for immunodetection of ‘Pneumocystis jirovecii’
This study aims to combine the production of a multi-epitope synthetic recombinant antigen (RSA) and an ELISA test for detection of anti-P. jirovecii antibodies, in order to develop a new approach for PcP diagnosis.
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Serological diagnosis of pneumocystosis: production of a synthetic recombinant antigen for immunodetection of ‘Pneumocystis jirovecii’
This study aims to combine the production of a multi-epitope synthetic recombinant antigen (RSA) and an ELISA test for detection of anti-P. jirovecii antibodies, in order to develop a new approach for PcP diagnosis.
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