Plasmodium vivax Chloroquine Resistance and Anemia in the Western Brazilian Amazon

In Latin America, data on chloroquine (CQ)-resistant Plasmodium vivax is limited, even with the current research efforts to sustain an efficient malaria control program in all these endemic countries, where malaria still is a major public health issue. This study estimated in vivo CQ-resistance in uncomplicated patients with P. vivax in use of CQ and primaquine simultaneously, in the Brazilian Amazon. From a total of 135 enrolled subjects, who accomplished the 28-day follow-up, parasitological failure was observed in 7 (5.2%) patients, in which plasmatic CQ and desethylchloroquine (DCQ) concentrations were above 100ng/dL.
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