(1-3)-Beta-D-glucan in association with lactate dehydrogenase as biomarkers of Pneumocystis pneumonia (PcP) in HIV-infected patients
- Autores: Antunes F, Badura R, de Sousa B, Esteves F, Fernandes C, Gaspar JF, Lee CH, Matos O, Seringa M
- Ano de Publicação: 2014
- Journal: European Journal of Microbiology & Infectious Diseases
- Link: http://www.ncbi.nlm.nih.gov/pubmed/24487911
Pneumocystis pneumonia (PcP) is a major HIV-related illness caused by Pneumocystis jirovecii. Definitive diagnosis of PcP requires microscopic detection of P. jirovecii in pulmonary specimens. The objective of this study was to evaluate the usefulness of two serum markers in the diagnosis of PcP. Serum levels of (1-3)-beta-d-glucan (BG) and lactate dehydrogenase (LDH) were investigated in 100 HIV-positive adult patients and 50 healthy blood donors.