Non-antibiotics reverse resistance of bacteria to antibiotics.

• Autores: Amaral L, Kristiansen JE, Martins A, Thomsen VF, Viveiros M
• Ano de Publicação: 2010
• Journal: In vivo
• Link: http://www.ncbi.nlm.nih.gov/pubmed/20952744

BACKGROUND: Most clinical isolates that exhibit a multi-drug resistant phenotype owe that resistance to over-expressed efflux pumps. Compounds that are efflux pump inhibitors (EPIs) reduce or reverse resistance to antibiotics to which the bacterial strain is initially resistant. We have evaluated non-antibiotics to reduce resistance of commonly encountered bacterial pathogens to antibiotics. MATERIALS AND METHODS: […]
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