Order and disorder in viral proteins: new insights into an old paradigm.
- Autores: Alves, Carolina, Celso, Cunha
- Ano de Publicação: 2012
- Journal: Future Virology
- Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=4&SID=T1zdDDEYC1eBxhDSCne&page=1&doc=1
The conventional dogma stating that proteins must fold into a well-defined structure In order to display biological function is being challenged everyday as new data emerge on the relevance of disordered regions and intrinsically disordered proteins. Viral proteins in particular can benefit greatly from the conformational flexibility granted by partially folded or unfolded protein segments.