Population structure and evidence for bothclonality and recombination among Brazilian strains of the subgenus Leishmania(Viannia)
- Autores: Boité MC, Cupolillo E, Kuhls K, Mauricio I, Mello MN, Miles M, Schönian G, Schweynoch C, Silva SO, Wirth T
- Ano de Publicação: 2013
- Journal: PLoS Negleted Tropical Diseases
- Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814519/
Parasites of the subgenus Leishmania (Viannia) cause varying clinical symptoms ranging from cutaneous leishmaniases (CL) with single or few lesions, disseminated CL (DL) with multiple lesions to disfiguring forms of mucocutaneous leishmaniasis (MCL). In this population genetics study, 37 strains of L. (V.) guyanensis, 63 of L. (V.) braziliensis, four of L. (V.) shawi, six of L. (V.) lainsoni, seven of L. (V.) naiffi, one each of L. (V.) utingensis and L. (V.) lindenbergi, and one L. (V.) lainsoni/L. naiffi hybrid from different endemic foci in Brazil were examined for variation at 15 hyper-variable microsatellite markers.