Negeviruses found in multiple species of mosquitoes from southern Portugal: Isolation, genetic diversity, and replication in insect cell culture

Autores: Abecasis A, Carapeta S, de Almeida APG, de Matos AP, do Bem B, Esteves A, Lopes A, McGuinness J, Parreira R, Piedade J
Ano de Publicação: 2015
Journal: Virology
Link: http://www.ncbi.nlm.nih.gov/pubmed/26057025

In this report, an RT-PCR approach based on the use of degenerate primers allowed the identification of negeviruses in four different species of mosquitoes (Ochlerotatus caspius, Culex pipiens, Cx. theileri and Cx. univittatus) collected in southern Portugal. The genomes of two of these viruses, sequenced to full completion, were shown to encode all the proteins encoded by previously described negeviruses
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Virology

Negeviruses found in multiple species of mosquitoes from southern Portugal: Isolation, genetic diversity, and replication in insect cell culture

Horizontal gene transfer from human host to HIV-1 reverse transcriptase confers drug resistance and partly compensates for replication deficits

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