New WHO guidelines for treatment of gambiense human African trypanosomiasis including fexinidazole: substantial changes for clinical practice

• Autores: Andreas K Lindner, Veerle Lejon, François Chappuis, Jorge Seixas, Leon Kazumba, Michael P Barrett, Erick Mwamba, Olema Erphas, Elie A Akl, Gemma Villanueva, Hanna Bergman, Pere Simarro, Augustin Kadima Ebeja, Gerardo Priotto, Jose Ramon Franco
• Ano de Publicação: 2019
• Journal: The Lancet Infectious Diseases
• Link: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30612-7/fulltext

Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a parasitic infection that usually progresses to coma and death unless treated. WHO has updated its guidelines for the treatment of this infection on the basis of independent literature reviews and using the Grading of Recommendations Assessment, Development and Evaluation methodology. The first-line treatment options, pentamidine […]
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