Dynamics of cytokines and immunoglobulins serum profiles in primary and secondary Cryptosporidium parvum infection: Usefulness of Luminex® xMAP technology
- Autores: Borrego M, Codices V, de Sousa B, Lopes T, Martins C, Matos O, Novo C
- Ano de Publicação: 2013
- Journal: Experimental Parasitology
- Link: http://www.ncbi.nlm.nih.gov/pubmed/23178641
Infection by Cryptosporidium parvum triggers a complex array of innate and adaptive cell mediated immune response, playing an important role in controlling the infection. To date, there are no studies applying the Luminex® xMAP technology to determine profiles of cytokines and immunoglobulins in the context of an infection by C. parvum. In this study, we analyzed these immune mediators in the serum of immunocompetent mice inoculated with C. parvum oocysts, using Luminex, to understand how the immune system responds to an infection by this parasite.