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Home / Archives for Moreno-Cid JA

Moreno-Cid JA

Vaccination with proteins involved in tick-pathogen interactions reduces vector infestations and pathogen infection

  • Autores: Antunes S, de la Fuente J, Domingos A, Merino O, Moreno-Cid JA, Mosqueda J, Perez de la Lastra JM, Rodríguez S, Rosario-Cruz R
  • Ano de Publicação: 2013
  • Journal: Vaccine
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24084474

Tick-borne pathogens cause diseases that greatly impact animal health and production worldwide. The ultimate goal of tick vaccines is to protect against tick-borne diseases through the control of vector infestations and reducing pathogen infection and transmission. Tick genetic traits are involved in vector-pathogen interactions and some of these molecules such as Subolesin (SUB) have been shown to protect against vector infestations and pathogen infection.
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Mosquito Akirin as a potential antigen for malaria control

  • Autores: A, Costa M, Custodio, de la Fuente J, Domingos A, Moreno-Cid JA, Pinheiro-Silva R, Silveira H, Villar M
  • Ano de Publicação: 2014
  • Journal: Malaria Journal
  • Link: http://www.malariajournal.com/content/13/1/470

Recent evidences using Subolesin (SUB) and Akirin (AKR) vaccines showed a reduction in the survival and/or fertility of blood-sucking ectoparasite vectors and the infection with vector-borne pathogens. These experiments suggested the possibility of using AKR for malaria control.
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Tick capillary feeding for the study of proteins involved in tick-pathogen interactions as potential antigens for the control of tick infestation and pathogen infection

  • Autores: Alberdi P, Antunes S, Bell-Sakyi L, de la Fuente J, Domingos A, Fragkoudis R, Merino O, Moreno-Cid JA, Mosqueda J, Perez de la Lastra JM, Weisheit S
  • Ano de Publicação: 2014
  • Journal: Parasites & Vectors
  • Link: http://www.parasitesandvectors.com/content/7/1/42

Ticks represent a significant health risk to animals and humans due to the variety of pathogens they can transmit during feeding. The traditional use of chemicals to control ticks has serious drawbacks, including the selection of acaricide-resistant ticks and environmental contamination with chemical residues. Vaccination with the tick midgut antigen BM86 was shown to be a good alternative for cattle tick control. However, results vary considerably between tick species and geographic location.
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