Proteomic changes in HEK-293 cells induced by hepatitis delta virus replication
- Autores: Coelho AV, Cunha C, Mendes M, Pérez-Hernandez D, Vázquez J
- Ano de Publicação: 2013
- Journal: Journal of Proteomics
- Link: http://www.ncbi.nlm.nih.gov/pubmed/23770296
Hepatitis delta virus (HDV) infection greatly increases the risk of hepatocellular carcinoma in hepatitis B virus chronically infected patients. HDV is highly dependent on host factors for accomplishment of the replication cycle. However, these factors are largely unknown and the mechanisms involved in the pathogenicity of the virus still remain elusive.