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Home / Archives for Donnelly MJ

Donnelly MJ

Gene flow-dependent genomic divergence between Anopheles gambiae M and S forms.

  • Autores: Donnelly MJ, Pinto J, Steen K, Weetman D, Wilding CS
  • Ano de Publicação: 2012
  • Journal: Molecular Biology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Gene+Flow-Dependent+Genomic+Divergence+between+Anopheles+gambiae+M+and+S+Forms.

Anopheles gambiae sensu stricto exists as two often-sympatric races termed the M and S molecular forms, characterized by fixed differences at an X-linked marker. Extreme divergence between M and S forms at pericentromeric “genomic islands” suggested that selection on variants therein could be driving interform divergence in the presence of ongoing gene flow, but recent work has detected much more widespread genomic differentiation.
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The Culex pipiens complex in continental Portugal: distribution and genetic structure.

  • Autores: Almeida AP, Donnelly MJ, Gomes B, Novo MT, Parreira R, Pinto J, Sousa CA
  • Ano de Publicação: 2012
  • Journal: Journal of the American Mosquito Control Association
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=The+Culex+pipiens+complex+in+continental+Portugal%3A+Distribution+and+genetic+structure.

Portugal is a southern European country that displays favorable ecological conditions for the establishment of West Nile virus (WNV) transmission cycles. Competent mosquito vector species are present throughout the country.
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Field, genetic, and modeling approaches show strong positive selection acting upon an insecticide resistance mutation in Anopheles gambiae s.s

  • Autores: Barbosa S, Donnelly MJ, Egyir-Yawson A, Hastings I, Lynd A, Mitchell S, Pinto J, Weetman D
  • Ano de Publicação: 2010
  • Journal: Molecular Biology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Field%2C+genetic+and+modeling+approaches+show+strong+positive+selection+acting+upon+an+insecticide+resistance+mutation+in+Anopheles+gambiae+s.s

Alleles subject to strong, recent positive selection will be swept toward fixation together with contiguous sections of the genome. Whether the genomic signatures of such selection will be readily detectable in outbred wild populations is unclear. In this study, we employ haplotype diversity analysis to examine evidence for selective sweeps around knockdown resistance (kdr) mutations […]
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Geographic population structure of the African malaria vector Anopheles gambiae suggests a role for the forest-savannah biome transition as a barrier to gene flow

  • Autores: Caccone A, Charlwood JD, Della Torre A, Donnelly MJ, Egyir-Yawson A, Elissa N, Gomes B, Moreno M, Pinto J, Santolamazza F, Simard F, Vicente JL, Weetman D
  • Ano de Publicação: 2013
  • Journal: Evolutionary applications
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24062800

The primary Afrotropical malaria mosquito vector Anopheles gambiae sensu stricto has a complex population structure. In west Africa, this species is split into two molecular forms and displays local and regional variation in chromosomal arrangements and behaviors.
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Hybridization and population structure of the Culex pipiens complex in the islands of Macaronesia.

  • Autores: Almeida AP, Alves J, Donnelly MJ, Gomes B, Pinto J, Santa-Ana M, Silva TL, Sousa CA, Vieira I
  • Ano de Publicação: 2012
  • Journal: Ecology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Hybridization+and+population+structure+of+the+Culex+pipiens+complex+in+the+islands+of+Macaronesia.

The Culex pipiens complex includes two widespread mosquito vector species, Cx. pipiens and Cx. quinquefasciatus. The distribution of these species varies in latitude, with the former being present in temperate regions and the latter in tropical and subtropical regions.
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Gene flow-dependent genomic divergence between Anopheles gambiae M and S forms.

  • Autores: Donnelly MJ, Pinto J, Steen K, Weetman D, Wilding CS
  • Ano de Publicação: 2011
  • Journal: Molecular Biology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Gene+flow-dependent+genomic+divergence+between+Anopheles+gambiae+M+and+S+forms

Anopheles gambiae sensu stricto exists as two often-sympatric races termed the M and S molecular forms, characterized by fixed differences at an X-linked marker. Extreme divergence between M and S forms at pericentromeric “genomic islands” suggested that selection on variants therein could be driving interform divergence in the presence of ongoing gene flow, but recent work has detected much more widespread genomic differentiation.
Ler mais

Feeding patterns of molestus and pipiens forms of Culex pipiens (Diptera: Culicidae) in a region of high hybridization

  • Autores: Almeida AP, Arez E, Calderón I, Donnelly MJ, Gomes B, Pinho L, Pinto J, Sousa CA, Vicente JL
  • Ano de Publicação: 2013
  • Journal: Parasites and Vectors
  • Link: http://www.parasitesandvectors.com/content/6/1/93

Two biological forms of the mosquito Culex pipiens s.s., denoted pipiens and molestus, display behavioural differences that may affect their role as vectors of arboviruses. In this study, the feeding patterns of molestus and pipiens forms were investigated in Comporta (Portugal), where high levels of inter-form admixture have been recorded.
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