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Home / Archives for Mendes T

Mendes T

Randomly amplified polymorphic DNA (RAPD) polymerase chain reaction assay for comparison of Schistosoma mansoni strains sensitive and resistant to praziquantel.

  • Autores: Afonso A, Belo S, Calado M, Clemente I, Ferreira CC, Ferreira PM, Figueira AR, Grácio MA, Mauricio I, Mendes T, Santos R
  • Ano de Publicação: 2011
  • Journal: Tropical Medicine & International Health
  • Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=2&SID=2CbhBUDoSw8ZkFBEQLW&page=1&doc=1

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Immunological and genetical analysis of combined therapy with artemisinin-praziquantel in Schistosoma mansoni in vivo.

  • Autores: Afonso A, Belo S, Calado M, Clemente I, Ferreira CC, Ferreira PM, Figueira AR, Graco MA, Mauricio I, Mendes T
  • Ano de Publicação: 2011
  • Journal: Tropical Medicine & International Health
  • Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=1&SID=2CbhBUDoSw8ZkFBEQLW&page=1&doc=1

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Trichinella spiralis: genome database searches for the presence and immunolocalization of protein disulphide isomerase family members

  • Autores: Clemente I, Freitas CP, Mendes T, Novo C
  • Ano de Publicação: 2014
  • Journal: Journal of Helminthology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25475092

The formation of nurse cells in host muscle cells during Trichinella spiralis infection is a key step in the infective mechanism. Collagen trimerization is set up via disulphide bond formation, catalysed by protein disulphide isomerase (PDI). In T. spiralis, some PDI family members have been identified but no localization is described and no antibodies specific for T. spiralis PDIs are available. In this work, computational approaches were used to search for non-described PDIs in the T. spiralis genome database and to check the cross-reactivity of commercial anti-human antibodies with T. spiralis orthologues.
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The role of the immunological background of mice in the genetic variability of Schistosoma mansoni as detected by random amplification of polymorphic DNA

  • Autores: Afonso A, Belo S, Calado M, Cossa-Moiane IL, Ferreira PM, Mauricio I, Mendes T
  • Ano de Publicação: 2014
  • Journal: Journal of Helminthology
  • Link: http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=9992333

Schistosomiasis is a parasitic disease caused by flatworms of the genus Schistosoma. Among the Schistosomaspecies known to infect humans, S. mansoni is the most frequent cause of intestinal schistosomiasis in sub-Saharan Africa and South America: the World Health Organization estimates that about 200,000 deaths per year result from schistosomiasis in sub-Saharan Africa alone. The Schistosoma life cycle requires two different hosts: a snail as intermediate host and a mammal as definitive host.
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