Immunoproteomic analysis of Plasmodium falciparum antigens using sera from patients with clinical history of imported malaria
- Autores: Costa RM, De Sousa KP, Nogueira F, Silva MS, Vitorino R
- Ano de Publicação: 2013
- Journal: Malaria Journal
- Link: http://www.malariajournal.com/content/12/1/100
The malaria caused by Plasmodium falciparum remains a serious public health problem in the world, due largely to the absence of an effective vaccine. There is a lack of information on the structural properties and antigens capable of activating the immunological mechanisms for the induction of protective immunity. Therefore, the objective of this study is to evaluate the serological reactivity of sera from individuals with imported malaria and identify major immunogenic proteins.