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Home / Archives for Abecasis AB

Abecasis AB

Science in court: the myth of HIV fingerprinting.

  • Autores: Abecasis AB, Albert J, Geretti AM, Power L, Vandamme AM, Weait M
  • Ano de Publicação: 2011
  • Journal: The Lancet Infectious Diseases
  • Link: http://www.sciencedirect.com/science/article/pii/S1473309910702838?np=y

An Editorial in Nature has emphasised the importance of proper scientific validation of forensic methods before their use in court. Classic fingerprinting, DNA fingerprinting, and brain imaging were discussed, and several cases of doubtful interpretation of forensic evidence with potentially incorrect conviction or exoneration of suspects were indicated.
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Molecular Epidemiological Analysis of Paired pol/env Sequences from Portuguese HIV Type 1 Patients

  • Autores: Abecasis AB, Camacho RJ, Carvalho AP, Costa I, Diogo I, Gomes P, Martins A, Portuguese Hiv-1 Resistance Study Group
  • Ano de Publicação: 2011
  • Journal: AIDS Research and Human Retroviruses
  • Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=5&SID=P2WA5hwy5j35Sqjoq2z&page=1&doc=1

The advent of new therapeutic approaches targeting env and the search for efficient anti-HIV-1 vaccines make it necessary to identify the number of recombinant forms using genomic regions that were previously not frequently sequenced.
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HIV-1 sub- type distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

  • Autores: Abecasis AB, Albert J, Åsjö B, Balotta C, Beshkov D, Boucher CB, Camacho RJ, Clotet B, De Gascun C, Griskevicius A, Grossman Z, Hamouda O, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, Theys K, Van de Vijver DMC, Vandamme AM, Vercauteren J, Wensing AMJ
  • Ano de Publicação: 2013
  • Journal: Retrovirology
  • Link: http://www.retrovirology.com/content/10/1/7

Understanding HIV-1 subtype distribution and epidemiology can assist preventive measures and clinical decisions. Sequence variation may affect antiviral drug resistance development, disease progression, evolutionary rates and transmission routes.
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A genomic signature and the identification of new sporulation genes

  • Autores: Abecasis AB, Alves R, Henriques AO, Pereira-Leal JB, Quintais L, Serrano M
  • Ano de Publicação: 2013
  • Journal: Journal of Bacteriology
  • Link: http://jb.asm.org/content/195/9/2101.full

Bacterial endospores are the most resistant cell type known to humans, as they are able to withstand extremes of temperature, pressure, chemical injury, and time. They are also of interest because the endospore is the infective particle in a variety of human and livestock diseases.
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Bridging epidemiology with population genetics in a low incidence MSM-driven HIV-1 subtype B epidemic in Central Europe

  • Autores: Abecasis AB, Kamer P, Lunar MM, Pecavar B, Poljak M, Tomazic J, Vandamme A-M, Volcansek G, Vovko TD
  • Ano de Publicação: 2015
  • Journal: Bmc Infectious Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25887543

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Lack of evidence for the selection of E138 mutations by first-generation non-nucleoside reverse transcriptase inhibitors in patients infected with HIV-1 non-B subtypes

  • Autores: Abecasis AB, Theys K, Van Laethem K
  • Ano de Publicação: 2015
  • Journal: Aids
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25909833

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Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

  • Autores: Abecasis AB, Albert J, Åsjö B, Balotta C, Beshkov D, Boucher CA, Camacho RJ, Clotet B, Coughlan S, Frentz D, Griskevicius A, Grossman Z, Hamouda O, Horban A, Jørgensen LB, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, Van de Vijver DA, Van Wijngaerden E, Vercauteren J, Wensing AM
  • Ano de Publicação: 2014
  • Journal: Bmc Infectious Diseases
  • Link: http://www.biomedcentral.com/1471-2334/14/407

One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data from the European Spread program.
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Novel HIV-1 recombinants spreading across multiple risk groups in the United Kingdom: the identification and phylogeography of Circulating Recombinant Form (CRF) 50_A1D

  • Autores: Abecasis AB, Ambrose JC, Delpech VC, Fearnhill E, Foster GM, Geretti AM, Hué S, Leigh Brown AJ
  • Ano de Publicação: 2014
  • Journal: PLoS One
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24454702

An increase in non-B HIV-1 infections among men who have sex with men (MSM) in the United Kingdom (UK) has created opportunities for novel recombinants to arise and become established. We used molecular mapping to characterize the importance of such recombinants to the UK HIV epidemic, in order to gain insights into transmission dynamics that can inform control strategies.
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