High GUD incidence in the early 20 century created a particularly permissive time window for the origin and initial spread of epidemic HIV strains
- Autores: de Sousa JD, Lemey P, Müller V, Vandamme AM
- Ano de Publicação: 2010
- Journal: PLoS One
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=High+GUD+Incidence+in+the+Early+20(th)+Century+Created+a+Particularly+Permissive+Time+Window+for+the+Origin+and+Initial+Spread+of+Epidemic+HIV+Strains
The processes that permitted a few SIV strains to emerge epidemically as HIV groups remain elusive. Paradigmatic theories propose factors that may have facilitated adaptation to the human host (e.g., unsafe injections), none of which provide a coherent explanation for the timing, geographical origin, and scarcity of epidemic HIV strains.