• Skip to primary navigation
  • Skip to content
  • Skip to footer
  • Estudantes
    • Webmail
    • Moodle
    • Ensino à Distância
    • NetP@
    • Biblioteca
    • Escola Doutoral
    • Serviços Académicos
    • Trabalhar no IHMT
  • Staff
    • Webmail
    • Área de Docentes
    • Área de Não-Docentes

IHMT

Instituto de Higiene e Medicina Tropical

PortuguêsEnglishFrançaisDeutschEspañol

Universidade Nova de Lisboa

  • Ensino
    • Doutoramentos
    • Mestrados
    • Ensino à Distância
    • Cursos de Especialização
    • Cursos de Curta Duração
    • Apoio ao Desenvolvimento
  • Investigação
    • GHTM
  • Doenças Tropicais
    • Glossário
    • Consulta do Viajante
    • Museu
      • Peça do Mês
    • Vídeos
    • MosquitoWeb
  • Unidades de Ensino e de Investigação
  • 5º Congresso Nacional de Medicina Tropical
Home / Archives for Maia C

Maia C

Elucidating in vitro and in vivo phenotypic behaviour of L. infantum/L. major natural hybrids

  • Autores: Albuquerque-Wendt A, Campino L, Carvalho M, Cortes S, de Freitas L A R, dos-Santos W L C, Lima I A, Maia C
  • Ano de Publicação: 2018
  • Journal: Parasitology
  • Link: https://doi.org/10.1017/S0031182018001993

The clinical manifestation and course of Leishmania infections depend on factors such as species, virulence and host-immunity. Although trypanosomatids are considered to have clonal propagation, genetic hybridization has produced successful natural hybrid lineages. Hybrids displaying strong selective advantages may have an impact on pathogenesis and the ecoepidemiology of leishmaniasis. Thus, characterization of phenotypic properties of Leishmania hybrids could bring significant insight into the biology, infectivity, pathogenicity and transmission dynamics of these atypical strains.
Ler mais

In vitro and in vivo behaviour of sympatric Leishmania (V.) braziliensis, L. (V.) peruviana and their hybrids.

  • Autores: Campino L, Cortes S, Cristovao JM, Esteves C, Maia C, Mauricio I, Miles M
  • Ano de Publicação: 2012
  • Journal: Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=In+vitro+and+in+vivo+behaviour+of+sympatric+Leishmania+(V.)+braziliensis%2C+L.+(V.)+peruviana+and+their+hybrids.

Leishmania (Viannia) braziliensis is the main cause of highly disfiguring mucocutaneous leishmaniasis (MCL) in South America. The related species L. (V.) peruviana has only been identified in simple cutaneous lesions (CL). Hybrids between L. braziliensis and L. peruviana have been reported although genetic exchange in Leishmania is considered to be rare. Here we compared growth in vitro, adaptive capacity under thermal and oxidative stress and behaviour in a hamster model, of L. braziliensis, L. peruviana, and their putative hybrids. At 24°C, the optimal temperature for in vitro growth, L. braziliensis had the highest growth rate.
Ler mais

Cytokine and Phenotypic Cell Profiles of Leishmania infantum Infection in the Dog.

  • Autores: Campino L, Maia C
  • Ano de Publicação: 2012
  • Journal: Journal of Tropical Medicine
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Cytokine+and+phenotypic+cell+profiles+of+Leishmania+infantum+infection+in+the+dog.

Leishmaniasis has reemerged in recent years showing a wider geographic distribution and increased global incidence of human and canine disease than previously known. Dogs are the main domestic/peridomestic reservoir hosts of zoonotic visceral leishmaniasis caused by Leishmania infantum.
Ler mais

EPIDEMIOLOGY OF LEISHMANIASES IN PORTUGAL

  • Autores: Campino L, Maia C
  • Ano de Publicação: 2010
  • Journal: Acta Medica Portuguesa
  • Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=6&SID=Z1yZbyGlNxI3xGo9eDj&page=1&doc=1

Leishmaniases, caused by the intracellular protozoan Leishmania infantum, are an endemic zoonosis in the Mediterranean basin. Dogs are considered the major host for these parasites, and the main reservoir for human visceral infection.
Ler mais

In vitro drug susceptibility of Leishmania infantum isolated from humans and dogs

  • Autores: Campino L, Henriques S, Maia C, Marques M, Nunes M, Rolão N
  • Ano de Publicação: 2013
  • Journal: Experimental Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/23747751

Visceral leishmaniasis (VL) caused by parasites of Leishmania donovani complex is a severe human disease which often leads to death if left untreated. Domestic dogs are the main reservoir hosts for zoonotic human visceral infection caused by Leishmania infantum. In the absence of effective human and dog vaccines, the only feasible way to treat and control leishmaniasis is through the use of suitable medications.
Ler mais

Antimony resistance and environment: Elusive links to explore during Leishmania life cycle.

  • Autores: Ait-Oudhia K, Maia C, Sereno D
  • Ano de Publicação: 2012
  • Journal: International Journal for Parasitology: Drugs and Drug Resistance
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Antimony+resistance+and+environment%3A+elusive+links+to+explore+during+Leishmania+life+cycle.

Leishmania drug resistance and particularly antimony resistance still continues to emerge in different part of the world. Because visceral and cutaneous leishmaniasis are transmitted in foci with zoonotic or anthroponotic life-cycles, the link between chemotherapeutic resistance and the selection for drug resistance, through drug consumption, cannot be as obvious for all forms of leishmaniasis.
Ler mais

Leishmania infection and host-blood feeding preferences of phlebotomine sandflies and canine leishmaniasis in an endemic European area, the Algarve Region in Portugal

  • Autores: Afonso MO, Campino L, Cristovao JM, Dionísio L, Maia C, Neto L
  • Ano de Publicação: 2013
  • Journal: Memorias do Instituto Oswaldo Cruz
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/23827997

The Algarve Region (AR) in southern Portugal, which is an international tourist destination, has been considered an endemic region of zoonotic leishmaniasis caused by Leishmania infantum since the 1980s. In the present study, phlebotomine and canine surveys were conducted to identify sandfly blood meal sources and to update the occurrence of Leishmania infection in vectors and dogs.
Ler mais

Non-classic metallointercalators with dipyridophenazine: DNA interaction studies and leishmanicidal activity

  • Autores: Campino L, de Sousa B, Farrell N, Madureira J, Maia C, Marques M, Ramos CIV, Santana-Marques MG
  • Ano de Publicação: 2013
  • Journal: Inorganic Chemistry
  • Link: http://pubs.acs.org/doi/abs/10.1021/ic401067d

[Cu(II)(dppz)2(AcOO)]+ and [Zn(II)(dppz)2]2+ bind DNA by intercalation and covalent binding modes. A loss of a dppz unit, which occurs only when DNA is present, justifies such dual binding mode.
Ler mais

Cytokine and Phenotypic Cell Profiles of Leishmania infantum Infection in the Dog.

  • Autores: Campino L, Maia C
  • Ano de Publicação: 2011
  • Journal: Journal of Tropical Medicine
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Cytokine+and+phenotypic+cell+profiles+of+Leishmania+infantum+infection+in+the+dog

Leishmaniasis has reemerged in recent years showing a wider geographic distribution and increased global incidence of human and canine disease than previously known. Dogs are the main domestic/peridomestic reservoir hosts of zoonotic visceral leishmaniasis caused by Leishmania infantum.
Ler mais

Can domestic cats be considered reservoir hosts of zoonotic leishmaniasis?

  • Autores: Campino L, Maia C
  • Ano de Publicação: 2011
  • Journal: Trends in Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Can+domestic+cats+be+considered+reservoir+hosts+of+zoonotic+leishmaniasis%3F

Canine and human zoonotic leishmaniasis caused by Leishmania infantum, which is transmitted by the bite of infected phlebotomine sand flies, is a serious public health problem in the Mediterranean basin and Latin America.
Ler mais

  • Page 1
  • Page 2
  • Page 3
  • Next Page »

Footer

  • Sobre o IHMT
  • Organização
  • Docentes e Investigadores
  • Serviços Académicos
  • Recursos Humanos
  • Trabalhar no IHMT
  • Instrumentos de Gestão
  • Associação de Alunos e Amigos
  • Parcerias
  • Biblioteca
  • Biobanco GHTM-IHMT – Biotropical Resources
  • Ensino
  • Investigação
  • Cooperação e Desenvolvimento
  • Qualidade

Contactos

Rua da Junqueira, 100
1349-008 Lisboa
Portugal
+351 213 652 600
+351 213 632 105

Contactos dos Serviços

Marcação de consultas:
+351 213 652 630/90
+351 213 627 553
medicina.viagens@ihmt.unl.pt

Subscrever newsletter

Follow us

  • Facebook
  • LinkedIn
  • YouTube
© Copyright 2021 IHMT-UNL Todos os Direitos Reservados.
  • Universidade Nova de Lisboa
  • Fundação para a Ciência e a Tecnologia

    Project UID/Multi/04413/2013

We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok