HIV-1 protease mutation 82M contributes to phenotypic resistance to protease inhibitors in subtype G.
- Autores: Camacho RJ, Covens K, Palma AC, Snoeck J, Van Laethem K, Vandamme AM
- Ano de Publicação: 2012
- Journal: Journal of Antimicrobial Chemotherapy
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=HIV-1+protease+mutation+82M+contributes+to+phenotypic+resistance+to+protease+inhibitors+in+subtype+G
The purpose of this study was the qualitative and quantitative assessment of the in vitro effect of HIV-1 protease (PR) mutation 82M on replication capacity and susceptibility to the eight clinically available PR inhibitors (PIs).